We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guests today are Jamie Luu, RDN, LDN, Strategy and Nutrition Manager, and Ronja Krieger, Chief Nutritionist at Almased. The Almased-type diet can boost natural satiety signals via GLP-1 and PYY — that is real and meaningful. But the new GLP-1-RA drugs go much further: they hijack those same signals, ramp them much higher, and translate into large weight losses in patients with obesity. So the diet is a “natural nudging” of the system; the drugs are a strong “override” of the system.
Check out the main topics of discussion for this episode of the Life Sciences Today podcast:
- You’re showing that the Almased high-protein diet raised GLP-1 and PYY levels — how would you compare that to what we know about the injectable GLP-1 drugs (like Ozempic)? Is the mechanism the same, just a different scale, or is there something qualitatively different going on?
- I read the IIS paper from 2021 and the results are impressive. Given that the diet intervention was isocaloric (same calories) and short-term, yet still changed appetite-hormone profiles — is Almased complementary to GLP-1 drugs like Ozempics or a preventive/maintenance tool for people who aren’t yet eligible for—or don’t want—drugs?
- For someone who isn’t on GLP-1 medication, what are realistic expectations of using a high-protein total diet replacement in terms of appetite regulation, hormone effects, and perhaps weight maintenance? And how should they view that in the context of the new drug therapies that dominate headlines?
Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.
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